Charlotte Roughton
“Hi there, I’m Charlotte. I live in Newcastle upon Tyne and I’m currently a Microbiology PhD student at Newcastle University.
I’m obsessed with microbes, especially bacteria, with my research interests lying within virulence – what mechanisms underpin it, and how these can be exploited to find novel treatments (especially important now with the concerning rise of antibiotic resistance). I’m currently working on the bacterium Clostridioides difficile, an antibiotic resistant superbug and the most common cause of hospital-acquired infections in Europe. Its ability to form dormant spores that are resistant to heat, radiation, and common disinfectants makes it extremely difficult to remove from the environment and is the main method by which it both infects new patients and re-infects current ones. Despite this, sporulation remains poorly understood and unexploited as a therapeutic target, with my project aiming to further unravel the molecular mechanisms underpinning this process.
I’m also autistic. I was diagnosed when I was two, for which I’m so grateful as so many autistic women fall under the radar and remain undiagnosed until adulthood. It provided an explanation for why I felt so different and struggled socially. However, growing up was difficult. While my family life was great and I always felt loved and accepted, the same could not be said for my social life. I was incredibly socially naïve, which in turn made me vulnerable to manipulation and malicious behaviour. Most of my childhood friendships were abusive. I never fit in or felt accepted by my peers. I felt ashamed, like I’d failed at being a “normal” human being, and as result hid the bullying from my family and developed a deep-rooted resentment towards myself and my diagnosis. This continued all the way into my undergraduate years, with me developing an unhealthy reliance on alcohol to try and maintain a false extroverted persona I thought I needed to be accepted, disordered eating, and eventually a diagnosis of depression and anxiety. Somehow, I graduated with a 2:1.
It wasn’t until I started my research Masters that I finally started to genuinely accept myself and become more at peace with being autistic. I ended the toxic relationship that I was in, stopped trying to maintain a completely unsustainable persona, and met some truly wonderful friends I felt completely at ease being my authentic self with. I now feel comfortable and safe openly disclosing being autistic. It still comes with its difficulties – I’m still working through my self-esteem issues, and my mental health needs continuous care and management to help prevent relapse. However, overall, I think being autistic is an asset – it has shaped who I am as a person, and makes me a better scientist.“
Instagram: @stitchingscience
Twitter: @cgroughton